Katherine Marie Heigl (born November 24, 1978) is an American actress and producer. She is possibly best known for her role as Dr. Izzie Stevens on ABC's Grey's Anatomy (2005-2010) for which she won a Primetime Emmy Award for Outstanding Supporting Actress – Drama Series in 2007. She has also starred in films such as Knocked Up, Zyzzyx Road, 27 Dresses, The Ugly Truth, Killers, and Life As We Know It.